HDD

My desktop is a Dell, duo core, 32 bit, Win Vista Home, has 350 Gig HDD, 4 Meg RAM, and I think that McAfee is making this situation occur, but am not sure. Lately, the HDD seems to be always accessing. Actually, when I boot up (and recently my icons don't stay where I put them on the desktop, and that bugs me also) the HDD will at some point begin constant accessing. It spins at a medium speed, the faster then back to medium, slow, then wicked fast, etc...., It seems to be when I open Google Chrome and this is all been happening within in the past 2-4 months. Anyway, when I open Google the HDD begins accessing. It acts as though it's looking or scanning for something, or defragging. I ran the Win FIXIT gadget program, no help. Went to Command Prompt, ran ChkDsk, no help, Command Prompt again, ran FSC / scannnow, no help. Ran the Clean Drive file from Windows Accessories, no help. I did shut off the McAfee BACKUP Program, which I didn't know was running, and that did seem to help, for awhile. I found this running on the Task Manager.
When I look at Task Manager, Processes, I see the explorer.exe file can be up to 140,000 K in the Memory (Private Working Set) and up to 50% CUP.

When it's not accessing (like on a fresh boot and before I go tot Google, the same file is around 15,000 K and 2% CPU usage.

Has anyone see where McAfee (or explorer.exe) accesses the HDD a lot? On that thought, I turned off McAfee SCANNER and the Automatic Updates, which also did seem to help. The Automatic Updates really slows down my machine. So much so that I think it's hung up and have left the room for a soda while waiting to get mouse control back.

Any help would be greatly appreciated
:confused: