Safely remove hardware prompt

Hello

I hope someone out there can help me because this has been driving me mad for months now!

I have a Dell laptop, with Windows vista. For a while now, the 'Safely remove software' keeps popping up, asking me to do this, although there is nothing to remove! As the prompt comes up with a (very annoying) sound, this is making it very difficult to work....

Thank you in advance :)